Synaptic plasticity and mood disorders
نویسندگان
چکیده
منابع مشابه
Neuronal plasticity and survival in mood disorders.
Studies at the basic and clinical levels demonstrate that neuronal atrophy and cell death occur in response to stress and in the brains of depressed patients. Although the mechanisms have yet to be fully elucidated, progress has been made in characterizing the signal transduction cascades that control neuronal atrophy and programmed cell death and that may be involved in the action of antidepre...
متن کاملEnhancing synaptic plasticity and cellular resilience to develop novel, improved treatments for mood disorders
There is mounting evidence that recurrent mood disorders - once considered "good prognosis diseases"- are, in fact, often very severe and life-threatening illnesses. Furthermore, although mood disorders have traditionally been conceptualized as neurochemical disorders, there is now evidence from a variety of sources demonstrating regional reductions in central nervous system (CNS) volume, as we...
متن کاملsynaptic neuronal plasticity
context the current study aimed to review research articles concerning cortical representational plasticity following the manipulations of inputs. evidence acquisition this review article compromised previous studies in pubmed, google scholar and scientific information databases according to the keywords since 1988. results ca1 neurons depolarization paired with ca3 presynaptic input result in ...
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لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملNeuronal plasticity: a link between stress and mood disorders.
Although stress represents the major environmental element of susceptibility for mood disorders, the relationship between stress and disease remains to be fully established. In the present article we review the evidence in support for a role of neuronal plasticity, and in particular of neurotrophic factors. Even though decreased levels of norepinephrine and serotonin may underlie depressive sym...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 2002
ISSN: 1359-4184,1476-5578
DOI: 10.1038/sj.mp.4001016